Frank and Emma attempt to locate a girl who escapes from a mental institution while Emma’s father grows ill.

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A MANHUNT ENSUES WHEN AN ESCAPEE FROM A MENTAL INSTITUTION–WHO IS BELIEVED TO HAVE DECAPITATED TWO PEOPLE–GOES ON THE RUN WITH A DEPUTY POLICE OFFICER.

As alarms blare, twenty-two year old Cassie Doyle escapes from a mental institution and makes her way to a nearby road. She stops a passing police car and tells Deputy Joe McNulty that someone is trying to kill her. The deputy begins to suspect otherwise, but before he can react, Cassie grabs the gun from his holster and points it at his head. Meanwhile, an African-American man places several items–including a headless chess piece and several paper palms–inside a wooden box and mails it to Emma.

Agent Baldwin is assigned to investigate the brutal murder of a nursing orderly who worked in the mental hospital where Cassie was interned. It is believed that the missing Cassie is responsible for the orderly